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This enzyme achieves this promiscuity primarily through rapid transpersulfidation of C201 in a CstB-unique loop relative to a canonical PDO, followed by molecular shuttling of a covalently bound sulfonate group to a persulfidated C408, and thiosulfate release

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For inflammatory and mechanical presentations, M10.061 and M10.062 cover idiopathic gout of the right and left knee, M05.661 covers rheumatoid arthritis of the right knee with involvement of other organs and systems, and M25.361 and M25.362 cover stiffness of the right and left knee, not elsewhere classified